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2023 Vol.27, Issue 4 Preview Page

Original Article

Comparative Analysis of Pre-formed 3D-Printed PCL/β-TCP Membrane Versus Collagen Membrane for Guided Bone Regeneration: A Preliminary Pilot Study
Subramanian Keerthana1
,
Jae-Hun Kim2
,
Hyun-Wook An3
,
Jin-Hyung Shim4
,
Jae-Hong Lee5**
,
Jeong-Ho Yun6*
1Postgraduate Student, Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University, Jeonju, Korea
2Postgraduate Student, Department of Mechanical System Engineering, Graduate School of Knowledge-based Technology and Energy, Tech University of Korea, Siheung-si, Gyeonggi-do, Korea
3Director, Research & Development Center, MEGAGEN Implant Co., Ltd, Daegu, Korea
4Professor, Department of Mechanical Engineering, Tech University of Korea, Siheung-si, Gyeonggi-do, Korea
5Associate Professor, Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University and Research Institute of Clinical Medicine of Jeonbuk National University- Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
6Professor, Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University and Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
*Corresponding Author
**Co-Corresponding Author
31 December 2023. pp. 182-195
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Abstract

Purpose: This study aimed to assess and compare the effectiveness of 3D-printed pre-formed resorbable polycaprolactone/β-tricalcium phosphate (PCL/β-TCP) membrane and collagen membrane, combined with demineralized bovine bone mineral (DBBM), for guided bone regeneration (GBR) for peri-implant dehiscence defects.

Materials and Methods: Twelve patients underwent GBR using either a PCL/β-TCP membrane with DBBM (PM group) or a collagen membrane with DBBM (CM group). Clinical assessments, including measurements of vertical defect height and width after implant placement (baseline) and re-entry surgery, were conducted. Cone-beam computed tomography imaging was performed to measure the augmented horizontal bone width (HW0, HW2, and HW4 at 0, 2, and 4 mm apical to the implant shoulder), vertical thickness (VT), and VT at a 45° angle (VT-45) at both time points.

Results: No adverse effects, such as soft tissue dehiscence, membrane exposure, or severe postoperative complications, were observed during the healing period. The mean reductions in the defect height and width were 89% and 80% in the PM group and 73% and 71% in the CM group, respectively. The horizontal bone width and vertical thickness between the two groups were statistically significant (p < .05) at HW0, VT, and VT-45, both at baseline and re-entry surgery. Meanwhile, the changes in bone augmentation between baseline and re-entry surgeries were not significantly different (p > .05) between the two groups.

Conclusion: Based on the findings of this study, pre-formed resorbable 3D-printed PCL/β-TCP membrane with DBBM could be an effective treatment option for peri-implant dehiscence defects, providing stability and vertical and horizontal bone augmentation.

Keywords
Alveolar ridge augmentation
Cone-beam computed tomography
Dental implants
3D printing
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Information
  • Publisher :The Korean Academy of Oral & Maxillofacial Implantology
  • Publisher(Ko) :대한구강악안면임플란트학회
  • Journal Title :Journal of implantology and applied sciences
  • Journal Title(Ko) :대한구강악안면임플란트학회지
  • Volume : 27
  • No :4
  • Pages :182-195
  • Received Date : 2023-12-07
  • Revised Date : 2023-12-27
  • Accepted Date : 2023-12-27
  • DOI :https://doi.org/10.32542/implantology.2023021
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