Comparison of Healing of Allograft and Autogenous Bone Implanted in the Skull Defect of Beagle Dog: Preliminary Animal Study

Jung-Gon Lee; Sang-Yun Kim; Pil-Young Yun; Young-Kyun Kim

doi:10.32542/implantology.20180006

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2018 Vol.22, Issue 2 Next Page

Original Article

Comparison of Healing of Allograft and Autogenous Bone Implanted in the Skull Defect of Beagle Dog: Preliminary Animal Study 비글견의 두개골 결손부에 이식한 동종골과 자가골의 치유 비교: 예비 동물 실험

30 June 2018. pp. 72-79

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Abstract

Purpose: The purpose of this study was to evaluate the healing process after autogenous and allogenous bone grafts for calvarial bone defects in beagles.

Materials and Methods: Two defects were formed in the skulls of two beagles and then grafted with a freeze-dried bone allograft (Double-Oss) and an autogenous bone chip, respectively. The clinical, radiographic, and histomorphometric examination results of the specimens taken 4 and 8 weeks after bone grafting were analyzed.

Results: The clinical, radiographic, and histological assessments revealed that 4 and 8 weeks after transplant, the beagle that received an autogenous bone graft was more likely to have high new bone formation than the beagle that had an allogenous bone. Four weeks after the transplant, the proportions of new bone formation were 11.5% and 35.8% in the allogenous and autogenous bones, respectively. Eight weeks after the transplant, the proportion of new bone formation with the allogenous bone increased significantly to 41.4% but was still less than the 65.6% with the autogenous bone.

Conclusion: The amount of new bone formation was smaller and the formation rate was slower with allogenous bone graft than with autogenous bone graft.

Keywords

Allogenous bone

Autogenous bone

Bone graft

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Information

Publisher :The Korean Academy of Oral & Maxillofacial Implantology
Publisher(Ko) :대한구강악안면임플란트학회
Journal Title :Implantology
Journal Title(Ko) :대한구강악안면임플란트학회지
Volume : 22
No :2
Pages :72-79
Received Date : 2018-06-04
Revised Date : 2018-06-17
Accepted Date : 2018-06-29
DOI :https://doi.org/10.32542/implantology.20180006

Journal of implantology and applied sciences ISSN:2765-7833(Print) 2765-7841(Online) 대한구강악안면임플란트학회지

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